🌍 African Neuroinformatics  ·  GRASP · DSI Africa

From Spice
to Synapse

Three free AI tools that screen any African medicinal plant as a drug candidate for stroke and dementia — in seconds. No coding. No login. No cost.

40+African plants in the database
8Neurodegeneration targets screened
FreeNo login · no cost · works offline
<1sResults — instant, no API wait
Three AI Tools

Pick a Tool. Start Now.

All three tools live inside one file. Open it once and every module works — online or offline, on any device.

MODULE 01
🔬
Plant → Drug Screener

Type any African medicinal plant or isolated compound. Get a complete drug-potential report — binding strength, safety profile, disease targets, and a plain-English summary — in under one second.

  • Predicted binding against AChE, BACE1, NF-κB, NRF2 and 4 more neuro targets
  • Full drug-likeness check — can it become a pill?
  • Blood-brain barrier penetrance prediction
  • Disease pathway map — Alzheimer's, stroke, or both
  • Lead grade (A / B / C) with collaboration recommendation
Open Plant Screener →
MODULE 02
🧬
Virtual Preclinical Cohort

Generate a complete virtual animal study before running a single real experiment. Predict biomarker responses, statistical power, and expected AI classification accuracy — saving months and reducing animal use.

  • Predicted biomarker trajectories across all treatment groups
  • Statistical power analysis and recommended sample size
  • Reduces required real animals by up to 60%
  • NC3R-compliant ethical benefit statement
  • Expected ML accuracy benchmarked against validated data
Open Virtual Cohort →
MODULE 03
🤖
Human Trial Simulator

The bridge between animal data and the first human dose. Predict safe starting dose, Phase I adverse events, Phase II efficacy, IND readiness, and NAFDAC regulatory pathway — before any patient is enrolled.

  • Allometric dose scaling — rat to human (FDA method)
  • Phase I safety simulation with dose escalation
  • Phase II efficacy prediction and sample size
  • West African population pharmacogenomics included
  • IND readiness score (0–100) + NAFDAC pathway
Open Trial Simulator →
How it works

Four Steps. Any Plant. Instant Result.

1
Open the platform

Click the button. One HTML file opens in your browser — no installation, no account.

2
Type your plant

Enter any African plant name or compound. The database covers 40+ plants — or estimates from any input.

3
Click Run

Results appear instantly — binding scores, safety profile, disease targets, network map.

4
Read the report

Plain-English summary tells you the lead grade, next lab step, and who to collaborate with.

Who it's for

Built for Every Level

You do not need to be a computational biologist. If you know a plant — you can use this.

👨‍🔬
Pharmacologists & Wet-lab Researchers

Use the screener to rank compounds before spending months in the lab. The tool tells you which plant is worth the assay — and which isn't.

🏥
Clinicians & Neurologists

The human trial simulator maps preclinical data to clinical endpoints you already know — ADAS-Cog, NIHSS, biomarker panels — before any patient is enrolled.

🎓
Students & Postgraduates

Run your plant through all three modules and you have a computational chapter for your thesis — with methods, results, and interpretations already structured.

🌿
Ethnobotanists & Herbalists

You know the plant. We know the biology. Type the name and find out which diseases it could treat and what the science says about why it works.

📊
Grant Writers & PIs

The platform generates preliminary computational data, power analysis, and IND readiness scores — all citable in a TETFund, DSI Africa, or Wellcome application.

🤝
African Research Groups

Each institution picks a plant, runs the pipeline, adds to the growing African natural products evidence base. The platform is the shared methodology.

Open Science · Open Collaboration

Ready to screen your plant?

The platform is free, open, and works on any device. No account. No installation. No cost. Just open it and type the name of any African plant you care about.

neuromatrixbiosystems.com/spice-to-synapse
Collaboration
Wet-lab enzyme assays · Clinical cohort studies · Bioinformatics extensions · Journal co-authorship · Grant partnerships
Supported by
GRASP · DSI Africa
African NeuroHealth Research Laboratory (ANHRL) Initiative
Platform
No API · No cost · Works offline
40+ African plants · 8 neuro targets · 3 modules